产品描述
| 溶解性 |
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| 存贮条件 | 储存温度-20°C |
| 应用 | An inhibitor xanthine oxidase and xanthine dehydrogenase |
| 产品介绍 | Febuxostat (非布司他; TEI 6720;TMX 67 ) 是选择性黄嘌呤氧化酶（XO）抑制剂，Ki为0.6 nM。还有研究报道称，它能够抑制LPS诱导的TNF-α、VCAM-1、MMP9和MCP-1表达。 |
| 备注 | Febuxostat is a non-purine selective xanthine oxidase inhibitor with IC50 of 114 -210 nM. |
| 生化机理 | Febuxostat is a potent non-purine xanithine oxidase inhibitor. Febuxostat is used in urate lowering therapies (ULTs) for the treatment of gout. |
| 别名 | 非布索坦; 2-[3-氰基-4-异丁氧基苯基]-4-甲基噻唑-5-甲酸；2-(3-氰基-4-异丁氧基苯基)-4-甲基-1,3-噻唑-5-羧酸 ;TEI 6720; TMX 67; Uloric; FBX; 2-(3-Cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic Acid；Adenuric；Atenuri |
