产品描述
| 熔点 | 267-269 °C |
| 溶解性 |
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| 存贮条件 | 储存温度-20°C |
| 应用 | A synthetic glucocorticoid VEGF inhibitor. |
| 产品介绍 | Fluocinolone Acetonide是一种皮质类固醇，与胞浆中糖皮质激素受体结合。 |
| 备注 | Fluocinolone Acetonide is a corticosteroid that binds to the cytosolic glucocorticoid receptor. |
| 生化机理 | Fluocinolone Acetonide is a synthetic glucocorticoid which acts as an inhibitor of tumor cells. Studies indicate that Fluocinolone Acetonide can inhibit promotion of tumor cells at an early stage of promotion if combined with a promoting agent. In addition, studies suggest that Fluocinolone Acetonide can regulate lipid metabolism by modulating gene expression. Alternate studies show that Fluocinolone Acetonide can inhibit the expression of VEGF (vascular endothelial growth factor) in the retinal pigment epithelial cell line due to its high glucocorticoid receptor affinity. Furthermore, Fluocinolone Acetonide can inhibit TNF-α angiogenesis. |
| 别名 | 乙酸肤轻松;仙乃乐;醋酸肤轻松;醋酸氟轻松; 6α,9α-二氟-11β,16α,17α,21-四羟基-1,4-妊娠双烯-3,20-二酮;6α,9α-二氟-16α-羟基泼尼松龙16,17-缩丙酮 6α-氟代曲安奈德;6α,9α-Difluoro-11β,16α,17α,21-tetrahydroxy-1,4-pregnadiene-3,20-dione;6α,9α-Difluoro-16α-hydroxyprednisolone 16,17-acetonide;6α-Fluorotriamcinolone acetonide;Sinalar;Synandone |
