熔点 | 138.0 - 142.0℃ |
溶解性 | Soluble in water (<1 mg/ml at 25 °C), ethanol (61 mg/ml at 25 °C), and DMSO (61 mg/ml at 25 °C). |
密度 | 1.0500 |
应用 | A triazole broad-spectrum antifungal agent. |
产品介绍 | Fluconazole是一种羊毛甾醇14 alpha去甲基化酶 抑制剂,抑制了麦角固醇的形成,用于治疗和预防浅表性和全身性真菌感染。 |
备注 | Fluconazole is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections. |
生化机理 | Fluconazole is a triazole broad-spectrum antifungal agent which is effective against Candida spp., cryptococcus neoformans and dermatophytes. Fluconazole is an inhibitor of CYP2C19, CYP2C9 and CYP3A4. |
别名 | 氟康唑; 2-(2,4-二氟苯基)-1,3-双(1H-1,2,4-三唑-1-基)-2-丙醇;UK 49858; UK49858; UK-49858;2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol; |