熔点 | 167-180°C |
折光率 | 1.62 |
溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
应用 | A tyrosine kinase inhibitor |
产品介绍 | Erlotinib, Free Base, is the free base form of erlotinib hydrochloride (sc-202154), a small molecule EGFR/HER-1 (human epidermal growth factor receptor) tyrosine kinase reversible inhibitor. |
生化机理 |
Erlotinib hydrochloride (trade name Tarceva;NSC 718781; OSI 744; R 1415 ) is a drug used to treat non-small cell lung cancer, pancreatic cancer and several other types of cancer. Erlotinib hydrochloride (trade name Tarceva;NSC 718781; OSI 744; R 1415 ) is a reversible tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR). It is marketed in the United States by Genentech and OSI Pharmaceuticals and elsewhere by Roche. |
别名 | NSC 718781;OSI-744;R-1415;OSI744;OSI 744;R1415;R 1415;埃罗替尼; N-(3-乙炔苯基)-[6,7-二(2-甲氧基乙氧基)]喹唑啉-4-胺;NSC 718781;OSI-744;R-1415;OSI744;OSI 744;R1415;R 1415;N-(3-Ethynylphenyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amine; 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline; Tarceva |