溶解性 |
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存贮条件 | 储存温度-20°C |
产品介绍 | Clindamycin palmitate HCl是一种水溶性的Clindamycin酯的盐酸盐形式,是一种棕榈酸,是一种林可酰胺类抗生素。 |
备注 | Clindamycin palmitate HCl is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic. |
生化机理 | Clindamycin palmitate HCl is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic. Clindamycin palmitate HCl is a bacterial protein synthesis inhibitor by inhibiting ribosomal translocation, in a similar way to macrolides. Clindamycin palmitate HCl does so by binding to the 50S rRNA of the large bacterial ribosome subunit. Clindamycin palmitate HCl inhibits protein synthesis in susceptible bacteria at level of 50S ribosome, thereby inhibiting peptide bond formation and causing cell death. |
别名 | 克林霉素棕榈酸酯盐酸盐;Clindamycin palmitate hydrochloride;methyl 7-?chloro-?6,?7,?8-?trideoxy-?6-?[[[(2S,?4R)?-?1-?methyl-?4-?propyl-?2-?pyrrolidinyl]?carbonyl]?amino]?-?1-?thio-? 2-?hexadecanoate-L-?threo-?α-?D-?galacto-?octopyranoside,monohydrochloride |