熔点 | 204-208 °C |
溶解性 | , , , Soluble in DMSO (≥5 mg/ml,warmed), water (9l mg/ml), and ethanol (71 mg/ml). |
存贮条件 | 储存温度 2-8°C |
应用 | A broad-based antifungal agent which blocks ergosterol biosynthesis. |
生化机理 | Amorolfine is a broad-based antifungal agent with fungicidal effects against most fungi, dermatophytes and yeasts. Amorolfine blocks ergosterol biosynthesis by interfering with delta 14 reduction and the delta 7-8 isomerisation. |
别名 | 阿莫罗芬盐酸盐;4-(3-对叔戊基苯基-2-甲基丙基)-顺式-2,6-二甲基吗啉盐酸盐;盐酸阿莫洛芬;(2R,6S)-rel-4-[3-[4-(1,1-Dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine hydrochloride;Ro 14-4767/002;Loceryl; Amorolfin; Curanail |