产品描述
| 敏感性 | 对热敏感 |
| 溶解性 | Soluble in water (100 mg/ml at 25 °C), ethanol (50 mM), methanol (5 mg/ml), DMSO (100 mM), and DMF. |
| 存贮条件 | 储存温度-20°C |
| 应用 | Calcium-dependent lipopeptide antibiotic. |
| 产品介绍 | Daptomycin 是一种新型脂肽类抗生素。 |
| 备注 | Daptomycin is a novel lipopeptide antibiotic. |
| 生化机理 | Daptomycin is a lipopeptide antibiotic produced by Streptomyces roseosporus with reported in vitro bactericidal activity against gram-positive organisms. As a calcium-dependent antibiotic, Daptomycin has been reported to act on the cytoplasmic membrane and undergo a conformational change upon interaction with lipid membranes in a model system. After the conformational change occurs, the compound is inserted into the membrane and causes significant perturbations. Membrane depolarization and leakage occurs, causing death in susceptible organisms. |
| 别名 | 达托霉素;达妥霉素;Dapcin;Cubicin;LY146032; LY 146032; LY-146032 |
