溶解性 | DMSO 61 mg/mL Water 61 mg/mL Ethanol <1 mg/mL |
存贮条件 | 储存温度-20°C |
产品介绍 | Dexrazoxane HCl(ICRF-187, ADR-529)是一种心脏保护剂。 |
备注 | A cardioprotective agent |
生化机理 |
Dexrazoxane hydrochloride is a cardioprotective agent. As a derivative of EDTA, dexrazoxane chelates iron, thus reduce the number of metal ions complexed with anthracycline and, consequently, decrease the formation of superoxide radicals. This agent is used to protect the heart against the cardiotoxic side effects of anthracyclines, such as doxorubicin. It was speculated that dexrazoxane could be used for further investigation to synthesize new antimalarial drugs. From Wikipedia. |
别名 | 右雷佐生盐酸盐; 右丙亚胺盐酸盐;Cardioxane; Zinecard; ICRF-187 hydrochloride;(S)-4,4'-(1-Methyl-1,2-ethanediyl)bis-2,6-piperazinedione hydrochloride;Dexrazoxane hydrochloride |