产品描述
| 溶解性 | Soluble in water (<1 mg/ml at 25 °C), DMSO (75 mg/ml at 25 °C), ethanol (2 mg/ml at 25 °C), methanol, and ethyl acetate. |
| 存贮条件 | 储存温度-20°C |
| 应用 | A tridentate chelator that binds iron with high affinity |
| 产品介绍 | Deferasirox(Exjade) is a rationally-designed oral iron chelator. Its main use is to reduce chronic iron overload in patients who are receiving long-term blood transfusions for conditions such as beta-thalassemia and other chronic anemias. The half-life of deferasirox is between 8 and 16 hours allowing once a day dosing |
| 备注 | Deferasirox(Exjade) is a rationally-designed oral iron chelator. |
| 生化机理 | Tridentate iron chelator that is orally active. |
| 别名 | 地拉罗司;去铁斯若;地拉罗司-D4;4-[3,5-二(2-羟基苯基)-1,2,4-三唑-1-基]苯甲酸;4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic Acid; Exjade; ICL-670; ICL-670A; CGP-72670 |
