产品描述
| 熔点 | 183-186°C |
| 溶解性 | Soluble in DMSO (50 mg/ml), water (partly), methanol, ethanol (~3 mg/ml), and DMF (~30 mg/ml). |
| 存贮条件 | 储存温度 2-8°C |
| 应用 | A peroxisome proliferator and hypolipidaemic agent. |
| 产品介绍 | Bezafibrate 是第一个临床测试的双重pan-peroxisome proliferator-activated receptors (PPAR)（过氧化物酶体增殖物激活受体）联合激动剂 |
| 备注 | Bezafibrate is the first clinically tested dual and pan-PPAR co-agonism. |
| 生化机理 | Bezafibrate is a peroxisome proliferator and hypolipidaemic agent that is a derivative of clofibrate. Shown to be effective in preventing mammary tumors induced by radiation together with DES, possibly by reducing prolactin and triglyceride concentrations. Bezafibrate is an activator of PPARα, PPARβ, PPARγ and LPL. |
| 别名 | 对-4-氯苯甲酰-β-氨乙基苯氧]异丁酸;2-[4-[2-(4-氯苯甲酰胺基)乙基]苯氧基]-2-甲基丙酸;苯扎贝特;2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]isobutyric Acid;Bezalip; Cedur; BM15075 |
