产品描述
| 沸点 | 489.67° C at 760 mmHg |
| 熔点 | 220-225℃ |
| 折光率 | 1.56 |
| 溶解性 |
|
| 存贮条件 | 储存温度-20°C |
| 密度 | 1.0400 |
| 应用 | A selective agonist of retinoid X receptors |
| 产品介绍 | Bexarotene (贝沙罗汀; Targretin)是维甲酸X受体（RXR）激动剂，可作用于CTCL。 |
| 备注 | Bexarotene is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma. |
| 生化机理 |
Bexarotene (tradenamed Targretin) is an oral antineoplastic agent indicated by the U.S. Food and Drug Administration (FDA) (in 2000) for cutaneous T cell lymphoma. Bexarotene (tradenamed Targretin) has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma. Bexarotene (tradenamed Targretin) is a retinoid specifically selective for retinoid X receptors, as opposed to the retinoic acid receptors. |
| 别名 | 蓓萨罗丁;贝沙罗汀; 4-(1-(5,6,7,8-四氢-3,5,5,8,8-五甲基-2-萘基)乙烯基)苯甲酸;;Targretin;LGD-1069 ; SR-11247 ;LG 100069; LG 69; LGD 1069; RO 26-4455; Targret; Targretin; Targretyn; Targrexin;4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid |
