溶解性 | 25°C: DMSO 76 mg/mL; Water <1 mg/mL; Ethanol 17 mg/mL |
存贮条件 | 储存温度-20°C |
应用 | 5-HT R抑制剂 |
产品介绍 | Vortioxetine (Lu AA21004) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. IC50 Value: 15nM (5-HT1A); 33nM (5-HT1B); 3.7nM(5-HT3A); 19nM (5-HT7); 1.6 nM(SERT) Target: 5-HT receptor |
别名 | Lu AA 21004;沃替西汀;1-[2-(2,4-甲基苯硫基)苯基]哌嗪;Lu AA 21004; Vortioxetine;1-[2-(2,4-Dimethylphenylsulfanyl)phenyl]piperazine |