产品描述
| 溶解性 |
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| 存贮条件 | 储存温度-20°C |
| 产品介绍 | Tirofiban是非肽类，糖蛋白IIb/IIIa拮抗剂。 |
| 生化机理 | Tirofiban (MK-383, Aggrastat) is a nonpeptide derivative of tyrosine that selectively inhibits the GP-IIb/IIIa receptor, with minimal effects on the ɑvβ3 vitronectin receptor. It inhibits platelet aggregation of gel-filtered platelets induced by 10 μM ADP with IC50 of 9 nM, but the IC50 for inhibition of human umbilical vein adhesion to vitronectin, which depends on ɑvβ3 vitronectin receptors, is 62 μmol/L. |
| 别名 | 替罗非班; (2S)-2-(丁基磺酰氨基)-3-[4-[4-(4-哌啶基)丁氧基]苯基]丙酸;L700462; MK383；N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl-d6]-L-tyrosine； (2S)-2-(Butylsulfonylamino)-3-[4-[4-(4-piperidyl)butoxy]phenyl]propanoic acid |
