C12H10N6
应用 | An inhibitor of PI3-kinase |
产品介绍 | TG100713 is a pan-PI3K inhibitor against PI3Kγ, PI3Kδ, PI3Kα and PI3Kβ with IC50 of 50 nM, 24 nM, 165 nM and 215 nM, respectively |
生化机理 | TG 100713 is an inhibitor of PI3-kinase (IC50 values are 24, 50, 165 and 215 nM for PI3Kδ, γ, α and β isoforms respectively). TG 100713 also inhibits endothelial cell proliferation. |
别名 | TG 100713;TG 100713;3-(2,4-DiaMino-6-pteridinyl)-phenol |