产品描述
| 溶解性 | Soluble in DMSO (70 mg/mL at 25 °C), ethanol (70 mg/mL at 25 °C), and water (<1 mg/mL at 25 °C). |
| 存贮条件 | 储存温度2-8°C |
| 应用 | An SRPK1 inhibitor. |
| 产品介绍 | SRPIN340是选择性SRPK抑制剂，作用于SRPK1, Ki为0.89 μM ，对其他140多种激酶没有显著的抑制活性。 |
| 备注 | SRPIN340 is a selective SRPK inhibitor with Ki of 0.89 μM for SRPK1, showing no significant inhibitory activity against other >140 kinases.. |
| 生化机理 | SRPIN 340 is a selective inhibitor of serine–arginine protein kinase 1 (SRPK1), a protein kinase that phosphorylates proteins containing serine-arginine-rich domains. SRPIN 340 is competitive with ATP and does not inhibit other SRPKs significantly. |
| 别名 | N-[2-(1-哌啶基)-5-(三氟甲基)苯基]-4-吡啶甲酰胺;SRPIN 340;SRPIN-340;SRPK inhibitor;N-[2-(1-Piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide |
