产品描述
| 溶解性 |
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| 存贮条件 | 储存温度 2-8°C |
| 应用 | A selective SLC6A2 inhibitor. |
| 产品介绍 | Reboxetine mesylate是一种降低肾上腺素重新吸收的抑制剂，抑制[3H]小鼠下丘脑突触体对碘化钾的吸收量和[3H]5-HT小鼠纹状体突触对碘化钾吸收的Ki值分别为8.2nM和1070nM。 |
| 备注 | Reboxetine is a norepinephrine reuptake inhibitor with Ki of 8.2 nM. |
| 生化机理 | Reboxetine, Mesylate is a potent and selective inhibitor of SLC6A2 noradrenalin uptake (Ki values are 1.1, 129 and > 10,000 nM for rat SLC6A2, ST, and DAT, respectively). Reboxetine displays > 1000-fold selectivity over α-adrenoceptors, 5-HT, dopamine, and muscarinic ACh receptors. |
| 别名 | 瑞波西汀甲磺酸盐; 2-[(2-乙氧基苯氧基)苯甲基]吗啉甲磺酸盐;Edronax mesylate; Vestra mesylate; Davedax mesylate; FCE20124 mesylate; PNU155950E mesylate;2-[(2-Ethoxyphenoxy)phenylmethyl]morpholine mesylate |
