产品描述
| 敏感性 | 对热敏感 |
| 溶解性 | Soluble in DMSO (47 mg/ml), water (<1 mg/ml), ethanol (157 mg/ml), alcohols, and chloroform. |
| 存贮条件 | 储存温度2-8°C |
| 应用 | An antibiotic that inhibits RNA synthesis and activates PXR. |
| 产品介绍 | Rifaximin 是Rifamycin SV衍生的一种口服的，半合成的，非全身性抗生素，具有抗菌活性。 |
| 备注 | Rifaximin(Xifaxan), an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. |
| 生化机理 | Rifaximin is an antibiotic that inhibits RNA synthesis and acts as a PXR (pregnane-X-receptor) activator. The compound is a derivative of rifamycin that has been shown to act strongly against Enterococcus, Streptococcus and Staphylococcus, with less activity against Enterobacteriaceae. Rifaximin has been used in a variety of gastrointestinal and intestinal epithelial cell studies. |
| 别名 | 4-脱氧-4′-甲基吡啶并[1′,2′-1,2]咪唑并[5,4-c]利福霉素 SV;利福昔明;利福西亚胺;Xifaxan;2S-Acetyloxy-5,6,21,23-tetrahydroxy-27-methoxy-2,4,11, 16,20,22,24,26-octamethyl-2,7-(epoxypentoeleca(1,11,13)trienimino)benzofuro[4,5-e]pyride[1,2-a]benzimidazole-1,15(2H)-dione;4-Deoxy-4′-methylpyrido[1′,2′-1,2]imidazo[5,4-c]rifamycin SV;Rifacol |
