产品描述
| 溶解性 | 25°C: DMSO 45 mg/mL; Water <1 mg/mL; Ethanol <1 mg/mL |
| 存贮条件 | 储存温度-20°C |
| 产品介绍 | PR-619是一种非选择性的，可逆的的deubiquitinylating enzymes (DUBs)（去泛素化酶）抑制剂，EC50为1-20 μM。 |
| 生化机理 | PR-619 is a cell permeable broad spectrum deubiquitylating enzymes (DBUs) inhibitor. PR-619 induces the accumulation of polyubiquitylated proteins in cells without directly affecting proteasome activity. |
| 别名 | PR 619;PR619;2,6-二氨基-3,5-二硫氰基吡啶;2,6-Diamino-3,5-dithiocyanopyridine;PR 619;PR619; Thiocyanic acid C,C′-(2,6-diamino-3,5-pyridinediyl) ester; 2,6-Diaminopyridine-3,5-bis(thiocyanate) |
