产品描述
| 溶解性 | Soluble in water (>500 mg/ml), methanol, DMSO (2 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C). |
| 存贮条件 | 储存温度-20°C |
| 应用 | An antiviral agent |
| 产品介绍 | Oseltamivir phosphate 是一种竞争性神经氨酸酶抑制剂。 Oseltamivir phosphate (Tamiflu) is a competitive neuraminidase inhibitor. The prodrug oseltamivir phosphate (Tamiflu) is itself not virally effective; however, once in the liver, it is converted by natural chemical processes, hydrolysed hepatically to its active metabolite, the free carboxylate of oseltamivir (GS4071). Oseltamivir phosphate (Tamiflu) serves as a competitive inhibitor towards sialic acid, found on the surface proteins of normal host cells. By blocking the activity of the viral neuraminidase enzyme, oseltamivir phosphate (Tamiflu) prevents new viral particles from being released by infected cells. Oseltamivir phosphate (Tamiflu) is an antiviral drug that slows the spread of influenza (flu) virus between cells in the body by stopping the virus from chemically cutting ties with its host cell. |
| 备注 | Oseltamivir phosphate (Tamiflu) is a competitive neuraminidase inhibitor. |
| 生化机理 |
Active (orally) inhibitor of the influenze virus neuraminidase and converted to the active acid metabolite in vivo. Also demonstrates antiviral drung capabilities. Oseltamivir(GS 4104; GOP-A-Flu; GS 4104; Tamiflu-Free; Tamvir) is an antiviral drug. GS 4104; GOP-A-Flu; GS 4104; Tamiflu-Free; Tamvir slows the spread of influenza (flu) virus between cells in the body by stopping the virus from chemically cutting ties with its host cell; median time to symptom alleviation is reduced by 0.5–1 day. GS 4104; GOP-A-Flu; GS 4104; Tamiflu-Free; Tamvir is marketed under the trade name Tamiflu, and is taken orally in capsules or as a suspension. It has been used to treat and prevent influenza A virus and influenza B virus infection in over 50 million people since 1999. Oseltamivir(GS 4104; GOP-A-Flu; GS 4104; Tamiflu-Free; Tamvir) is useful for Antiviral agents. |
| 别名 | 磷酸奥司他韦; 达菲; (3R,4R,5S)-4-乙酰胺基-5-氨基-3-(1-乙基丙氧基)-1-环己烯-1-羧酸乙酯磷酸盐;Tamiflu; Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-pentan-3-yloxycyclohexene-1-carboxylate phosphate |
