熔点 | 260 °C |
敏感性 | 对热敏感 |
溶解性 | DMSO 1 mg/mL Water 21 mg/mL Ethanol <1 mg/mL |
存贮条件 | 储存温度 2-8°C |
应用 | Nefopam hydrochloride has been used as a standard for the quantitative determination of tramadol by gas chromatography-mass spectrometry (GC/MS). |
生化机理 | Nefopam is a centrally-acting analgesic drug of the benzoxazocine chemical class. Nefopam is a non-opioid, but has a potentiating effect on morphine and other opioids. Its mechanism of action is not certain, but may involve its action as a dopamine/serotonin/norepinephrine reuptake inhibitor. |
别名 | 盐酸奈福泮; 盐酸甲苯氧辛啶; 5-甲基-1-苯基-3,4,5,6-四氢-1H-2,5-氧氮苯并辛因盐酸盐;3,4,5,6-四氢-5-甲基-1-苯基-1H-2,5-氧氮苯并辛因 盐酸盐 ;3,4,5,6-四氢-5-甲基-1-苯基-1H-2,5-氧氮苯并辛因;3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine hydrochloride;5-Methyl-1-phenyl-1,3,4,6-tetrahydro-5H-benz[f]-2,5-oxazocine hydrochloride;Nefopam hydrochloride |