溶解性 |
|
存贮条件 | 储存温度-20°C |
备注 | HCV-796 is a specific inhibitor of HCV NS5B polymerase with IC50 of 0.01-0.14 μM for genotype 1, with EC50 of 5 nM and 9 nM against genotype 1a and 1b replicons. |
生化机理 |
Nesbuvir, a novel selective nonstructural protein 5B (NS5B) polymerase inhibitor, act as candidate for HCV treatment. |
别名 | 5-cyclopropyl-2-(4-fluorophenyl)-6-(N-(2-hydroxyethyl)methan-4-ylsulfonamido)-N-methylbenzofuran-3-carboxamide;5-cyclopropyl-2-(4-fluorophenyl)-6-(N-(2-hydroxyethyl)methan-4-ylsulfonamido)-N-methylbenzofuran-3-carboxamide |