产品描述
| 溶解性 | Soluble in water (100 mM), DMSO (100 mM), and ethanol (2 mg/ml) at 25 °C. |
| 存贮条件 | 储存温度-20°C |
| 应用 | A free radical trapping compound |
| 产品介绍 | NXY 059 is a free radical trapping compound that displays potential neuroprotective properties. |
| 备注 | NXY-059 is a novel nitrone, shows efficacious neuroprotective effects. |
| 生化机理 |
NXY-059 is the disulfonyl derivative of the neuroprotective spin trap phenylbutynitrone or "PBN". Both NXY-059, its parent PBN and their hydrolysis/oxidation product MNT are very powerful scavengers of free radicals. Unlike most antioxidants, this does not involve the further production of a reactive free radical. So they are particularly effective in terminating radical chain reactions. Likewise, unlike PBN and its derivatives, most reducing antioxidants can act as pro-oxidants. |
| 别名 | 神经保护药物 NXY 059;Disufenton sodium;1,3-Benzenedisulfonic acid, 4-[[(1,1-dimethylethyl)imino]methyl]-, N-oxide, disodium salt |
