产品描述
| 溶解性 |
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| 存贮条件 | 储存温度 2-8°C |
| 产品介绍 | ML-161是一种蛋白酶活化受体1 (PAR1)的别构抑制剂，对人血小板中血小板P-选择素表达抑制的IC50为0.26μM。 |
| 备注 | ML-161 is an allosteric inhibitor of PAR1 with IC50 of 0.26 μM. |
| 生化机理 | ML-161 is an antagonist of the protease-activated receptor 1 (PAR1), that inhibits thrombin and SFLLN-induced platelet activation. ML-161 dose dependently inhibits SFLLN-induced expression of P-selectin with an IC50 of 0.26 μM. |
| 别名 | 2-溴-N-[3-[(1-氧代丁基)氨基]苯基]苯甲酰胺;ML-161;2-Bromo-N-[3-[(1-oxobutyl)amino]phenyl]benzamide;ML-161 |
