产品描述
| 溶解性 | DMSO 93 mg/mL Water 8 mg/mL Ethanol 2 mg/mL |
| 存贮条件 | 储存温度-20°C |
| 产品介绍 | CHIR-99021 (CT99021) HCl是CHIR-99021的盐酸盐，是一种GSK-3α/β抑制剂，IC50为10 nM/6.7 nM，可用于区分GSK-3和其最接近的同源物的Cdc2和ERK2。 |
| 备注 | CHIR-99021 HCl (CT99021) is hydrochloride of CHIR-99021, which is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM; ability to distinguish between GSK-3 and its closest homologs Cdc2 and ERK2. |
| 生化机理 |
CHIR-99021 (CT99021) is a GSK-3 inhibitor, IC50= 7 nM |
| 别名 | CT99021;CHIR99021;CHIR 99021;CT-99021;6-[2-[4-(2,4-二氯苯基)-5-(4-甲基-1H-咪唑-2-基)嘧啶-2-基氨基]乙基氨基]吡啶-3-甲腈6-(2-(4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-ylamino)ethylamino)nicotinonitrile hydrochloride |
