产品描述
| 溶解性 |
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| 存贮条件 | 储存温度-20°C |
| 产品介绍 | CZC24832是第一个PI3Kγ选择性抑制剂，IC50为27 nM，比作用于PI3Kβ选择性高10倍，比作用于PI3Kα和PI3Kδ选择性高100倍以上。 |
| 备注 | CZC24832 is the first selective PI3Kγ inhibitor with IC50 of 27 nM, with 10-fold selectivity over PI3Kβ and >100-fold selectivity over PI3Kα and PI3Kδ. |
| 生化机理 |
CZC24832, is a selective inhibitor of phosphoinositide 3-kinase γ (PI3Kγ) with efficacy in in vitro and in vivo models of inflammation. |
| 别名 | 5-(2-氨基-8-氟[1,2,4]三唑并[1,5-a]吡啶-6-基)-N-(叔丁基)-3-吡啶磺酰胺;CZC 24832;CZC-24832;5-(2-Amino-8-fluoro[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-(tert-butyl)-3-pyridinesulfonamide |
