溶解性 | Soluble in DMSO (10 mg/ml), water (5 mg/ml), DMF (10 mg/ml), 95% ethanol, and 1N NaOH heating (30 mg/ml). |
应用 | A multi-use inhibitor that protects cerebellar granule cells from apoptosis. |
产品介绍 | 3-Methyladenine is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM; blocks class I PI3K consistently, whereas suppression of class III PI3K is transient, and also blocks autophagosome formation. |
备注 | 3-Methyladenine is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM; blocks class I PI3K consistently, whereas suppression of class III PI3K is transient, and also blocks autophagosome formation. |
别名 | 6-氨基-3-甲基嘌呤;3-MA;3-MA; 6-Amino-3-methylpurine; Autophagy Inhibitor |