产品描述
| 溶解性 | Soluble in DMSO (50 mM). |
| 存贮条件 | 储存温度 2-8°C |
| 应用 | A dual inhibitor of FAK (focal adhesion kinase) and PYK2. |
| 产品介绍 | PF-431396是双PYK2/FAK抑制剂，IC50分别为11nM和2 nM。 |
| 生化机理 | PF 431396 is a dual inhibitor of FAK (focal adhesion kinase) (IC50 of 2 nM) and proline-rich tyrosine kinase 2 (PYK2) (IC50 of 11 nM). |
| 别名 | PF 431396;PF431396;;N-甲基-N-[2-[[[2-[(2-氧代-2,3-二氢-1H-吲哚-5-基)氨基]-5-三氟甲基嘧啶-4-基]氨基]甲基]苯基]甲磺酰胺;PF 431396;PF431396;N-[2-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]phenyl]-N-methyl-Methanesulfonamide |
