产品描述
| 溶解性 | DMSO 74 mg/mL (200.31 mM); Water <1 mg/mL (<1 mM);Ethanol <1 mg/mL (<1 mM) |
| 存贮条件 | 储存温度-20°C |
| 应用 | A potent TGF beta RI inhibitor. |
| 产品介绍 | LY2157299是有效的TGFβ receptor I (TβRI)抑制剂，IC50为56 nM。Phase 2/3。 |
| 备注 | LY2157299 is a potent TGFβ receptor I (TβRI) inhibitor with IC50 of 56 nM. Phase 2. |
| 生化机理 | LY2157299 is a potent TGFβ RI I (transforming growth factor receptor beta 1) inhibitor. |
| 别名 | 4-[5,6-二氢-2-(6-甲基-2-吡啶基)-4H-吡咯并[1,2-b]吡唑-3-基]-6-喹啉甲酰胺;LY-2157299;LY 2157299;Galunisertib;4-[5,6-Dihydro-2-(6-methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinolinecarboxamide;4-(2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carboxamide |
