沸点 | 769.82 °C at 760 mmHg |
熔点 | 318.16 °C |
敏感性 | 对光线和湿度敏感,易吸潮 |
溶解性 | Soluble in DMSO (1 mg/ml), DMF (1 mg/ml), and methanol (2 mg/ml). |
存贮条件 | 储存温度-20°C |
密度 | 1.7800 |
应用 | An antibiotic and a strong inhibitor of protein kinase C (PKC) |
产品介绍 | K252B: an inhibitor of protein kinase A, C, G K-252b is a general, cell permeable protein kinase inhibitor which acts by binding to the ATP binding domain of the kinase. K-252b is a potent inhibitor of CaMKII (Ca2+/calmodulin kinase II), MYLK (myosin light chain kinase, Ki=0.147 μM), PKA (cAMP- dependent protein kinase, Ki=0.09 μM), PKC (protein kinase C, Ki=0.02 μM), and cGKI (cGMP-dependent protein kinase, Ki=0.1 μM). |
别名 | ;Staurosporine Aglycone |