熔点 | 255°C-270°C |
敏感性 | 对光线和湿度敏感,易吸潮 |
溶解性 | Readily soluble in chloroform, acetonitrile, acetone, dioxane, tetrahydrofuran, pyridine; soluble in ethanol, methanol, 1-propanol, ethyl acetate and n-butanol; insoluble in water, 2-propanol |
存贮条件 | 储存温度-20℃ |
应用 |
K252a is a highly potent cell permeable inhibitor of CaM kinase and phosphorylase kinase . At high concentrations it also inhibitors of serine/threonine protein kinases K252a inhibits tyrosine phosphorylation of Trk A induced by NGF K252a is reported to promote myogenic differentiation in C2 mouse myoblasts |
产品介绍 | K252a: Cell permeable protein kinase inhibitor |
别名 | ;Antibiotic K-252a; Antibiotic SF 2370; Protein Kinase Inhibitor;(8R*, 9S*, 11S*)-(-)-9-hydroxy-9-methoxycarbonyl-8-methyl-2,3,9,10-tetrahydro-8,11-epoxy-1H, 8H, 11H-2, 7b, 11a-triazadibenzo(a,g)cycloocta(cde)trinden-1-one |