产品描述
| 溶解性 | Soluble in ethanol, methanol, DMF, DMSO (≥ 10 mg/ml), and water (limited). |
| 存贮条件 | 储存温度 -20°C |
| 密度 | 1.1830 |
| 应用 | An antibiotic inhibitor of isoleucyl-tRNA synthetase |
| 产品介绍 | Pseudomonic Acid, also known as mupirocin, is an antibiotic isolated from Pseudomonas fluorescens which strongly inhibits protein and RNA synthesis. Inhibition of protein synthesis was reversed by isoleucine and Pseudomonic Acid was shown to inhibit IleRS (isoleucyl-tRNA synthetase) in vitro. Pseudomonic Acid also demonstrates weak inhibitory action on FARSL (phenylalanyl-tRNA synthetase). Efficacy against staphylococci and streptococci including multiply resistant Staphylcoccus aureus and Staphylococcus epidermidis is reported with Pseudomonic Acid. |
| 别名 | 莫匹罗星;假单胞菌酸;BRL 4910A;Pseudomonic acid;5,9-Anhydro-2,3,4,8-tetradeoxy-8-[[3-(2-hydroxy-1-methylpropyl)oxiranyl]methyl]-3-methyl-[2E,8[2S,3S(1S,2S)]]-L-talonon-2-enonic acid 8-carboxyoctyl ester |
