2-脱氧-D-葡萄糖

2-脱氧-D-葡萄糖

产品参数

货号 规格 操作
D109194-100g 咨询
D109194-1g 咨询
D109194-25g 咨询
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服务地域:全国

属性:产地:上海; 品牌:阿拉丁 ;货期:现货

上海阿拉丁生化科技股份有限公司

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属性

熔点 146-147°C
旋光率 46.5 ° (C=1, H2O)
溶解性 Soluble in water.
存贮条件 储存温度2-8℃
密度 1.5330

描述

应用 2-脱氧-D-葡萄糖(2-Deoxy-D-Glucose,2-DG)为天然抗代谢物类抗生素,具有能够抑制病毒感染、酵母发酵、致病菌及肿瘤细胞生长等。
产品介绍 溶于水和乙醇。
生化机理 2-Deoxy-D-Glucose (2-Deoxyglucose) is a glucose analog that inhibits glycolysis via its actions on hexokinase, the rate limiting step of glycolysis. It is phosphorylated by hexokinase to 2-DG-P which can not be further metabolized by phosphoglucose isomerase. This leads to the accumulation of 2-DG-P in the cell and the depletion in cellular ATP. In vitro, 2-Deoxyglucose has been shown to induce autophagy, increase ROS production, and activate AMPK
别名 2-去氧-D-葡萄糖;2-脱氧-D-葡糖;2-Deoxy-D-arabinohexose;2-Deoxyglucose
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