熔点 | 236 °C |
旋光率 | +5.0 to +7.0 deg(C=2、CHCl3) |
敏感性 | 对热敏感 |
溶解性 | Soluble in water. |
存贮条件 | 储存温度 -20°C |
应用 | Used to produce non-pyrogenic liposome capable of caging molecules |
产品介绍 | 通过单一水合步骤形成装载有选定分子的无热原、良好定义的脂质体。 1,2-Distearoyl-sn-glycero-3-phosphocholine is a non-pyrogenic phospholipid that has been shown to form well-defined liposomes that are capable of being loaded with a molecule of choice. This loading and vessicle formation is reportedly accomplished simply by a single hydration step. Research has shown that this encapsulation technique has been shown to increase the uptake for 125I-labelled polyvinylpyrrolidone by four times in an intestinal sac preparation from adult rats. More recently, compounds such as 5-fluorouracil ,cyclosporin A and celecoxib have been used in this lipid encapsulation technique. |
别名 | DSPC;1,2-双硬脂酰基-sn-丙三基-3-磷酸胆碱;磷酸(R)-2,3-双(硬脂酰氧基)丙基[2-(三甲基铵)乙基]酯;3- sn -磷脂酰胆碱,1,2-二硬脂酰, L-α-二硬脂酰磷脂酰胆碱, L-β,γ-二硬脂酰-α-卵磷脂, DSPC, PC(18:0/18:0), PC ;1,2-Dioctadecanoyl-sn-glycero-3-phosphocholine;3-sn-Phosphatidylcholine, 1,2-distearoyl L-α-Phosphatidylcholine, distearoyl L-β,γ-Distearoyl-α-lecithin;(R)-2,3-Bis(stearoyloxy)propyl [2-(Trimethylammonio)ethyl] Phosphate;1,2-Dioctadecanoyl-sn-glycero-3-phosphocholine;DSPC |