存贮条件 | 储存温度 -20°C |
应用 | A naturally occurring phospholipid involved in inflammation and other physiological processes. |
生化机理 | PAF C-18 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the de novo and remodeling pathways. PAF C-18 is less potent than PAF C-16 in the induction of platelet aggregation, but equipotent in activation of guinea pig macrophages. PAF C-18 induces the release of PGE2 and TXB2 from albumin-elicited guinea pig macrophages, and PAF C-18 enhances the spreading of plated macrophages. Pathological processes involving PAF include necrotizing enterocolitis, asthma, allergy and inflammation. |
别名 | 血小板活化因子(C18);C18-02:0 PC;[(2R)-2-Acetoxy-3-Octadecoxy-Propyl] 2-Trimethylammonioethyl Phosphate; [(2R)-2-Acetoxy-3-Octadecoxypropyl] 2-Trimethylammonioethyl Phosphate; [(2R)-2-Acetoxy-3-Stearyloxy-Propyl] 2-Trimethylammonioethyl Phosphate |