产品描述
| 存贮条件 | 储存温度 -20°C |
| 应用 |
· as an internal standard in the chromatography with negative ion electrospray ionization coupled to tandem mass spectrometry for myocardial ceramide quantification · as an internal standard for the ceramide quantification from rat samples using liquid chromatography-mass spectrometry · to test its effect on mitochondrial stress response in worms |
| 产品介绍 | Ceramide comprise sphingosine and fatty acid and belongs to the sphingolipids family |
| 生化机理 | C16 Ceramide levels are elevated in chronic alcohol-related liver disease (ALD). In general, ceramide inhibits mitochondrial function and insulin signaling. They are essential component of cell membrane and are involved in lipid raft formation. C16 ceramide based analog (C2-C16 CCPS) is potential anticancer agent used in chemotherapy. The levels of C16 ceramide and its ratio with other ceramides is regarded as a biomarker in predicting coronary artery disease (CAD). It interacts with the DNA-binding domain of tumor suppressor protein p53 and activates p53 |
| 别名 | (2S,3R,4E)-2-(棕榈酰氨基)-4-十八碳烯-1,3-二醇, N-[(1S,2R,3E)-2-羟基-1-（羟甲基）-3-庚烯-1-基]十六烷酰胺, N-棕榈酰-D-赤型-鞘氨醇, N-棕榈酰-D-鞘氨醇, C16-神经酰胺, C16神经酰胺(d18:1/16:0) ;C16 Ceramide (d18:1/16:0)； N-palmitoyl-D-erythro-sphingosine, powder； Cer(d18:1/16:0) |
