溶解性 | DMSO: >10 mg/mL |
存贮条件 | 储存温度-20℃ |
生化机理 | PalGly is an endogenous signaling lipid that modulates calcium influx and nitric oxide production. PalGly inhibits heat-evoked firing of wide dynamic range (WDR) neurons, activates calcium influx in DRG cells and stimulates NO production. Preliminary studies suggest its signaling mechanism involves GPCR-mediated cation channel activation and a Gαi/o-coupled signaling pathway, which is being further investigated. |
别名 | PalGly;PalGly;N-(1-Oxohexadecyl)glycine; N-Hexadecanoylglycine; Hexadecanoylaminoacetic acid; N-palmitoyl glycine |