产品描述
| 熔点 | 292°C |
| 折光率 | 268 |
| 旋光率 | 48°C |
| 敏感性 | 对热、光线敏感 |
| 存贮条件 | 储存温度2-8℃ |
| 生化机理 |
Gemcitabine hydrochloride is used for treatment of non-small cell lung cancer, pancreatic cancer, mammary cancer, ovarian cancer, bladder cancer, nasopharyngeal carcinoma and non-Hodgkin's lymphoma.Deoxycytidine analog that inhibits DNA synthesis. Metabolized to form gemcitabine triphosphate (dFdCTP) and gemcitabine diphosphate (dFdCDP). dFdCTD inhibits ribonucleotide reductase causing a reduction in cellular nucleotides. dFdCTP is incorporated in DNA resulting in DNA strand termination. It displays antitumor activity in vitro and in vivo. |
| 别名 | dFdC;2'-脱氧-2',2'-二氟胞苷 ;2′-Deoxy-2′,2′-difluorocytidine dFdC dFdCyd |
