产品描述
| 熔点 | 330°C |
| 溶解性 | Soluble in aqueous alkaline solutions (1.4 mg/ml), ethanol (~5 mg/ml), DMSO (7 mg/ml), 1eq. NaOH (5 mM), DMF (~20 mg/ml), 1:5 solution of DMF:PBS(pH7.2) (`~1 mg/ml), water (1 mg/ml) at 25 °C, and methanol. |
| 存贮条件 | 贮存温度2-8℃ |
| 密度 | 1.6540 |
| 应用 | An inhibitor of glutathione S-transferase and 15-LO. |
| 产品介绍 | Luteolin is an antioxidant flavonoid and a free radical scavenger. It inhibits rat liver cytosolic glutathione S-transferase activity and soybean and reticulocyte 15-LO (15-lipoxygenases). Luteolin also shows cytotoxic effects on Raji lymphoma cells. Incubation of the non-tumor cell line C3H10T?CL8 with luteolin results in induction of p53 accumulation and apoptosis, with apoptosis occurring at the G2/M phase of the cell cycle. Luteolin is an inhibitor of Cot, PDE1-5, c-Src, HDAC, Maltase-glucoamylase, Topo I, PKC ε, Fatty Acid Synthase, PPAR γ and MMP. |
| 别名 | 木犀草素;3',4',5,7-四羟基黄酮，黄色黄素，黄示灵，藤黄菌素3',4',5,7-Tetrahydroxyflavone |
