熔点 | 119°C(lit.) |
存贮条件 | 储存温度-20°C;贮藏条件下氩 |
生化机理 |
Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) is the hormonally active form of vitamin D.Active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) displays calcemic actions. Calcitriol stimulates intestinal and renal Ca2+ absorption and regulates bone Ca2+ turnover. Calcitriol (1,25-Dihydroxyvitamin D3; Rocaltrol )exhibits antitumor activity; Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells. |
别名 | 骨化三醇 二羟胆钙化醇 (5Z,7E)-(1S,3R)-9,10-开环胆甾-5,7,10(19)-三烯-1,3,25-三醇;1alpha,25-dihydroxycholecalciferol (5z,7e)-(1s,3r)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol 1α,25-Dihydroxyvitamin D3 |