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Eotaxin/CCL11 Protein, Mouse

MCE 国际站：Eotaxin/CCL11 Protein, Mouse

Eotaxin/CCL11 Protein, Mouse是嗜酸性粒细胞、嗜碱性粒细胞和Th2淋巴细胞的有效化学诱导剂。

Synonyms: rMuEotaxin/CCL11; C-C motif chemokine 11; Eosinophil chemotactic protein; SCYA11

Species: Mouse

Source: E. coli

Biological Activity: Full biological activity determined by a chemotaxis bioassay using purified eosinophils is in a concentration range of 100-1000 ng/mL.

研究背景：CCL11 is a small cytokine belonging to the CC chemokine family. CCL11 selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergicresponses. It is produced by IFN-γ-stimulated endothelial cells and TNF-activated monocytes. CCL11 is a potent chemoattractant for eosinophils, basophils, and Th2 lymphocytes. CCL11 has a number of important biological functions in disease processes. It plays a critical role in allergic and nonallergic inflammatory reactions, such as mycobacterial and schistosomal induced granulomatosis.

蛋白编号：P48298 (H24-P97)

基因 ID：20292

产品分类：细胞因子和生长因子  |  趋化因子  |  CC 趋化因子  |  趋化因子 CCL11

Categories：Cytokines and Growth Factors  |  Chemokine & Receptors  |  CC Chemokines  |  Eotaxin/CCL11

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