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Anal Biochem. 2008 Jul 1;378(1):43-52. doi: 10.1016/j.ab.2008.03.039. Epub 2008 Mar 28. Coupling of fully automated chip-based electrospray ionization to high-capacity ion trap mass spectrometer for ganglioside analysis. Almeida R1, Mosoarca C, Chirita M, Udrescu V, Dinca N, Vukelić Z, Allen M, Zamfir AD. Author information Abstract
NanoMate robot was coupled to a high-capacity ion trap (HCT) mass spectrometer to create a system merging automatic chip-based electrospray ionization (ESI) infusion, ultrafast ion detection, and multistage sequencing at superior sensitivity. The interface between the NanoMate and HCT mass spectrometer consists of an in-laboratory constructed mounting device that allows adjustment of the robot position with respect to the mass spectrometer inlet.
Automated chip-based nanoelectrospray Fully automated chip-based nanoelectrospray was performed on a NanoMate BiVersa robot incorporating ESI 400 chip technology (Advion Biosciences, Ithaca, NY, USA) controlled and manipulated by ChipSoft 7.1.1 software operating under a Windows system. The robot was coupled to the HCT Ultra mass spectrometer via an in-laboratory made mounting system.