Human Stem Cell Transcription Factors DNA Methylation PCR Array: EAHS-511Z The Human Stem Cell Transcription Factors EpiTect Methyl II Signature PCR Array profiles the promoter methylation status of a panel of 22 transcription factors whose association with stem cell differentiation and development has been well documented. Profiling cellular or fresh tissue genomic DNA samples with these arrays may help correlate CpG island methylation status with pluripotency and differentiation status. The results may also help provide insights into the molecular mechanisms and biological pathways behind development and differentiation. With a simple restriction enzyme digestion and real-time PCR, research studies can analyze the promoter methylation status of 22 different stem cell-related transcription factors with this DNA methylation PCR array.
Both 96-well and 384-well ( 4 X 96 ) formats are available.
The EpiTect Methyl II PCR Arrays use the MethylScreen™ Technology provided under license from Orion Genomics, LLC.     

Cell Cycle Regulators: NOTCH2, RB1.
Cell Differentiation Genes: ETS1, GATA2, HIF1A, JUN, NEUROD1, NOTCH2, OLIG2, PPARG, RB1, RUNX1, RUNX2, SMAD2, SOX2.
Chromatin Modification Genes: FOXP3, HIF1A, RB1, SOX2.
DNA Methylation Genes: FOS.
Environmental & Intracellular Stimuli Responses: ETS1, FOS, FOXP3, HIF1A, NEUROD1, PPARG, STAT1.
Developmental Regulators: AR, FOS, GATA2, NEUROD1, NOTCH2, OLIG2, PPARG, RUNX1, SMAD2, SOX2, STAT3.
Other Stem Cell Maintenance & Differentiation Genes: FOXA2, LIN28, NFYA, PCNA