应用领域:
检测样品:
检测项目:
前言:
Liquid chromatography-mass spectrometry (LC-MS) is a sensitive, accurate, and precise technique applied in clinical research for the analysis of a large number of compounds and metabolites from various drug classes, such as antidepressants, hypnotics, stimulants, cardiacs, and antihistamines. Thermo Scientific Transcend system powered by TurboFlow™ technology provides an alternative separation technique for complex biomatrices, simplifying sample preparation, increasing LC-MS/MS sensitivity, and reducing ion suppression.
仪器:
Thermo Scientific TSQ Quantum mass spectrometer
结论:
An efficient (9 minute), sensitive (LOQ of 1-50 ng/mL), and precise LC-MS/MS method using TurboFlow technology was developed for the quantitation of 30 drugs in human urine. In clinical research, TurboFlow technology simplifies sample preparation and improves method robustness and sensitivity.