前言：

　　Synthetic opioids have analgesic, antitussive and antiaddictive effects. However, they are also abused for their psychoactive effects and are often diverted from lawful prescriptions to unlawful recreational use. Simple, robust and precise analytical methods are needed to quantify these compounds in biological matrices for forensic purposes.

仪器：

Thermo Scientific TSQ Quantum mass spectrometer

结论：

　　A robust method with simple and easy sample preparation was developed and validated for forensic toxicology laboratories. The data window and total run time make this method amenable to multiplexing with the Thermo Scientific Transcend LX-2 LC system. Multiplexing with the Transcend™ LX-2 LC system would result in a run time of 2.5 minutes per sample.