| 应用 |
A strong norepinephrine reuptake inhibitor and weak serotonin reuptake inhibitor |
| 备注 |
Amoxapine is a tricyclic dibenzoxazepine (an N-aryl piperazine) which acts similarly to several other tricyclic antidepressants, amoxapine inhibits GLYT2a transport activity with IC50 of 92 μM. |
| 生化机理 |
inhibits uptake of norepinephrine; inhibits 5-HT2 serotonergic receptors. |
| 别名 |
阿莫沙平;2-氯-11-(1-哌嗪基)二苯并[b,f][1,4]氧氮杂卓;2-Chloro-11-(1-piperazinyl)dibenzo[b,f][1,4]oxazepine; 8-chloro-6-piperazin-1-ylbenzo[b][1,4]benzoxazepine |
