| 应用 |
A tridentate chelator that binds iron with high affinity |
| 产品介绍 |
Deferasirox(Exjade) is a rationally-designed oral iron chelator. Its main use is to reduce chronic iron overload in patients who are receiving long-term blood transfusions for conditions such as beta-thalassemia and other chronic anemias. The half-life of deferasirox is between 8 and 16 hours allowing once a day dosing |
| 备注 |
Deferasirox(Exjade) is a rationally-designed oral iron chelator. |
| 生化机理 |
Tridentate iron chelator that is orally active. |
| 别名 |
地拉罗司;去铁斯若;地拉罗司-D4;4-[3,5-二(2-羟基苯基)-1,2,4-三唑-1-基]苯甲酸;4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic Acid; Exjade; ICL-670; ICL-670A; CGP-72670 |
