| 应用 |
An SRPK1 inhibitor. |
| 产品介绍 |
SRPIN340是选择性SRPK抑制剂，作用于SRPK1, Ki为0.89 μM ，对其他140多种激酶没有显著的抑制活性。 |
| 备注 |
SRPIN340 is a selective SRPK inhibitor with Ki of 0.89 μM for SRPK1, showing no significant inhibitory activity against other >140 kinases.. |
| 生化机理 |
SRPIN 340 is a selective inhibitor of serine–arginine protein kinase 1 (SRPK1), a protein kinase that phosphorylates proteins containing serine-arginine-rich domains. SRPIN 340 is competitive with ATP and does not inhibit other SRPKs significantly. |
| 别名 |
N-[2-(1-哌啶基)-5-(三氟甲基)苯基]-4-吡啶甲酰胺;SRPIN 340;SRPIN-340;SRPK inhibitor;N-[2-(1-Piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide |
