Minoxidil
面议
药物分子

Minoxidil

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  • 阿拉丁
  • 上海
  • 生产商
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上海阿拉丁生化科技股份有限公司
高级会员 高级会员
产品特点
规格信息
货号 CAS号
M158689-5G 38304-91-5
M158689-100g 38304-91-5
M158689-1G 38304-91-5
M158689-25g 38304-91-5
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产品描述
  • 分子式 C9H15N5O
  • 分子量209.25
  • Beilstein号 25(5)12,317
  • EC号
  • MDL号 MFCD00063409
  • PubChem编号

属性

溶解性 Soluble in water (2.2 mg/ml), 100% ethanol (29 mg/ml), propylene glycol, acetone, DMSO (6.5 mg/ml), and methanol.

描述

应用 Minoxidil has been used as test drug:
· in dermal papilla spheroid model, to study the effectof hair regeneration
· administered orally to experimental rats, in theapproach to identify biomarkers of drug induced vascular injury
· administered via oral gavage to nonhuman primate modelin order to study its effect on tilt responses
生化机理 Minoxidil is originally used to treat hypertension,which also induces hypertrichosis. It is considered as a potent drug fortreating androgenetic alopecia.

Activates ATP-activated K+ channels;vasodilator; slow or stop hair loss and promote hair regrowth.
别名 6-(1-哌啶基)-2,4-嘧啶二胺 3-氧化物, 6-(1-哌啶基)嘧啶-2,4-二胺 3-氧化物;米诺地尔;2,6-二氨基-4-哌啶并嘧啶1-氧化物;;6-(1-Piperidinyl)-2,4-pyrimidinediamine;3-oxide 6-(1-Piperidinyl)pyrimidine-2,4-diamine 3-oxide;2,6-Diamino-4-piperidinopyrimidine 1-Oxide
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