货号 | CAS号 |
---|---|
G122413-100g | 60142-96-3 |
G122413-25g | 60142-96-3 |
G122413-500g | 60142-96-3 |
G122413-5g | 60142-96-3 |
熔点 | 166°C |
应用 |
Gabapentin has been used: · as the α2δ-ligand to examine whether the allyl isothiocyanate (AITC) sensitized thermal aversion assay might be useful as a screening method for the identification of presumptive analgesics · dissolved in uptake buffer which is used to measure the to measure ASP (trans-4-[4-(Dimethylamino)styryl]-1-methylpyridinium iodide) substrate by organic cation transporter type 2 (OCTN2) using liquid chromatography - mass spectrometry · used as an analgesic adjuvant for intraperitoneal injections |
生化机理 | 具镇惊作用,机制不明;可穿过血脑屏障,增加大脑中的GABA浓度,减少兴奋性氨基酸神经递质,也许是通过其对电压门控钙通道,具有镇痛,抗焦虑药,神经保护,抗痫作用。 |
别名 | 加巴喷丁; 1-(氨甲基)环己烷乙酸;1-(甲氨基)环己烷乙酸;Gabapentin; 1-(Aminomethyl)cyclohexaneacetic Acid |