N'-硝基-L-精氨酸(L-NNA)

属性

熔点	257°C
溶解性	Soluble in 0.1N HCl (moderately), and water (5 mM).

描述

应用	NO合成酶抑制剂
产品介绍	Nω-Nitro-L-arginine displays potent inhibition of NOS with selectivity for NOS1 and NOS3 over NOS2. It has been observed to inhibit endothelial nitric oxide biosynthesis and decrease radical generation of peroxynitrite ions. Other inhibitory effects demonstrated in experiments include blocking brady-kinin-induced relaxation in dog coronary artery strips and suppressing morphine tolerance in mice. N G-Nitro-L-arginine causes significant vasoconstriction and is utilized in studying nitric oxide as a neuronal messenger.
别名	L-NNA;Nω-硝基-L-精氨酸;L-NNA;H-Arg(NO2)-OH;NG-NO2-L-Arg;N5-(Nitroamidino)-L-2,5-diaminopentanoic acid

个人防护设备	Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter
WGK德国	3
安全声明（欧洲）	S22;S24/25;